Demain, S

Gonçalves, A. C.

Marques, Alda

Samuel, D

English

Repositório Institucional da Universidade de Aveiro

Ana Carolina Vieira Gonçalves; Dr. Alda Marques; Dr. Sara Demain; Dr. Dinesh SamuelIntroductionIt  is predicted that dementia will affect 42.3 million people worldwide  in 2020 [1]. In the UK, 820 000 people live with dementia [2], a figure forecasted to increase to 1 million by 2025 [1]. The National Institute for Health and Care Excellence, supported by a recent Cochrane review recommend physical activity for people with dementia [3,4]. Caution is still needed in the interpretation of positive results of physical activity in this population due to the heterogeneity of the available research [5]. This  heterogeneity impairs an effective synthesis of evidence and limits the development of clear recommendations for clinical practice [6]. MethodsConclusionsThis project will:i)  inform the design of clinical trials of exercise/physical activity including people with dementia and ii) provide guidance for health care professionals, assessing exercise/physical activity interventions for people with dementia, regarding the most appropriate outcomes and outcome measuresReferences[1] Hill, K.D., et al., Effectiveness of balance training exercise in people with mild to moderate severity Alzheimer's disease: protocol for a randomised trial. BMC Geriatr, 2009. 9: p. 29; [2] DoH, D.o.H., Living well with dementia: A National Dementia Strategy, DoH, Editor. 2009: UK.; [3] NICE, N.I.f.H.a.C.E., Dementia - Supporting people with dementia and their carers in health and social care, in NICE clinical guideline 42. 2006.; [4] Forbes, D., et al., Exercise programs for people with dementia. Cochrane Database of Systematic Reviews, 2013(12).; [5] Forbes, D., et al., Exercise programs for people with dementia (Review). The Cochrane Collaboration, 2015(4); [6] Macefield, R.C., et al., Developing core outcomes sets: methods for identifying and including patient-reported outcomes (PROs). Trials, 2014. 15(49); [7] Williamson, P.R., et al., Developing core outcome sets for clinical trials: issues to consider. Trials, 2012. 13(132). [a] http://www.telegraph.co.uk/news/health/news/11532982/Dementia-research-gets-13-times-less-funding-than-cancer-figures-show.htmlFaculty of Health Sciences and Solent NHS trust – 2015 Postgraduate Post Graduate Research Health Sciences conference, Southamptonwww.southampton.ac.ukDevelopment of a Core Outcome Set to evaluate physical activity in people with dementiaAimDevelopment of a Core outcome set to evaluate physical activity in people with dementia, applicable to exercise/physicalactivity interventions in all stages of the disease progression, across settings. Delphi surveyConsensus on outcomes to include in the core outcome set (distinctly mild to moderate and severe stages).Interviews / focus groupsExplore meaningful outcomes of physical activity from different stakeholders.Literature reviewlinking the outcomes agreed in the Delphi survey to the most appropriate outcome measures. Literature reviewsynthesise the outcomes of exercise/physical  activity in previous literature.+A Core Outcome Set is an agreed minimum collection of outcomes to be used as standard in interventions of a particular condition. Core Outcome sets allow direct comparison of the effects of different interventions, minimizing risk of outcome reporting bias and increasing the power of meta-analysis [7]. Figure 1: Representation of a person living with dementia. Available from: [a]Figure 2: diagram describing the 4 phases of the development of this core outcome set . 

Development of a core outcome set to evaluate physical activity in people with dementia

https://ria.ua.pt/bitstream/10773/27902/1/2015_Goncalves_Development%20of%20a%20Core%20Outcome.pdf

Development of a core outcome set to evaluate physical activity in people with dementia

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Repositório Institucional da Universidade de Aveiro