The disorders of processes of peroxide oxidation of proteins, lipids and antioxidant defense in the development of infertility in patients with chronic prostatitis on background of sexually transmitted infections

Abstract

We have studied indicators of oxidative stress (carbonyl derivatives and TBA-active products) and antioxidant protection (activity of superoxide dismutase) at infertile (140) and fertile (140) patients with chronic prostatitis on a background of sexually transmitted infections (STIs). The increase in activity of lipid peroxidation was revealed in the serum of infertile patients with chronic prostatitis, statistically significantly dependent on STI. Installed, the presence of mixed infection in infertile patients with chronic prostatitis is the most adverse factor that triggers the development of oxidative stress and contributing to its persistence