Conservative myomectomy is the unique treatment for women of reproductive period. Therefore it's very important to prevent recurrence of fibroids by individual antirecurrent treatment. Were examined 75 women, average age 32,4 ± 3,1 years, duration disease (fibroids) 4,29±1,5 years (from 2 to 7 years). Initial diameter of fibroids 45,82±20,76 mm, after conservative myomectomy 16,55±2,56 мм. Number of fibroids /per woman 5,18±2,5. Pharmacotherapy were provided with agonists of GnRH agonists, intrauterine levonorgestrel containing the depot - the system, antiprogestins. No significant deferens of efficiency depended from type of pharmacotherapy was found: decreased of volume of uterus, number of fibroids nodes, diameter of dominant node
