In functional magnetic resonance imaging (fMRI) analysis, many studies have been conducted on inter-subject variability as well as intra-subject reproducibility. These studies indicate that fMRI could have unique characteristics for individuals. In this study, we hypothesized that the dynamic information during 1 min of fMRI was unique and repetitive enough for each subject, so we applied long short-term memory (LSTM) using initial time points of dynamic resting-state fMRI for individual identification. Siamese network is used to obtain robust individual identification performance without additional learning on a new dataset. In particular, by adding a new structure called region of interest–wise average pooling (RAP), individual identification performance could be improved, and key intrinsic connectivity networks (ICNs) for individual identification were also identified. The average performance of individual identification was 97.88% using the test dataset in eightfold cross-validation analysis. Through the visualization of features learned by Siamese LSTM with RAP, ICNs spanning the parietal region were observed as the key ICNs in identifying individuals. These results suggest the key ICNs in fMRI could represent individual uniqueness
