la expression and RNA content in BALF and peripheral blood were evaluated on the condition of combination therapy of Cyclosporine (CsA), Azathioprine (Azp), and Predonine (Pr) following lung allotransplanatation in dogs. 1) la expression of lymphocytes in BALF was faciliated according to the appearance of rejection and depressed according to the disappearance of rejection. Thefore, it is indicated that la expression is one of the valuable monitorings to determine the appearance of rejection. 2) The low RNA content of macrophages in BALF and monocytes in the peripheral blood showed regardless of the appearance of rejection or not. It was of no use to determine rejection on the condition of prescribing CsA
