Membranous Nephropathy and Kimura\u27s Disease Manifesting a Hip Mass. A Case Report with Literature Review

Akosa AB, Sherif A, Maidment CG; Davenport A, Maciver AG, Hall CL, M; Day TA, Abreo F, Hoajsoe DK, Aarsta; Hui PK, Chan YW; Katagiri K, Itami S, Hatano Y, Yama; KIMURA OSAMU; Kimura T, Yoshimura S, Ishikawa E; Konishi N, Tamura T, Kawai C, Shira; Liu C, Hu W, Chen H, et al; Matsuda O, Makiguchi K, Ishibashi K; Matsumoto K, Katayama H, Hatano M; Qunibi WY, Al-Sibai MB, Akhtar M; Reed RJ, Terazakis N; Takebara K, Ogawa K, Iijima M, Hino; Tsukadaira A, Kitano K, Okubo Y, et; Yamada A, Mitsuhashi K, Miyakawa Y,; Yamamoto M, Matsuoka K, Kougo T, Ho

Membranous Nephropathy and Kimura\u27s Disease Manifesting a Hip Mass. A Case Report with Literature Review

Authors: Sherif A, Maidment CG Akosa AB
Maciver AG, Hall CL, M Davenport A
Abreo F, Hoajsoe DK, Aarsta Day TA
Chan YW Hui PK
Itami S, Hatano Y, Yama Katagiri K
KIMURA OSAMU
Yoshimura S, Ishikawa E Kimura T
Tamura T, Kawai C, Shira Konishi N
Hu W, Chen H, et al Liu C
Makiguchi K, Ishibashi K Matsuda O
Katayama H, Hatano M Matsumoto K
Al-Sibai MB, Akhtar M Qunibi WY
Terazakis N Reed RJ
Ogawa K, Iijima M, Hino Takebara K
Kitano K, Okubo Y, et Tsukadaira A
Mitsuhashi K, Miyakawa Y, Yamada A
Matsuoka K, Kougo T, Ho Yamamoto M
Publication date: 1 January 2010
Publisher: 'Japanese Society of Internal Medicine'
Doi

Abstract

We report a case of Kimura\u27s disease with membranous nephropathy. A 15-year-old Japanese boy was referred to our hospital with proteinuria and a subcutaneous mass in the hip. Renal biopsy demonstrated secondary membranous nephropathy (MN) with mild mesangial proliferation and some electron-dense deposits in the mesangium. Laboratory tests revealed eosinophilia and a high level of serum IgE, which are common findings in Kimura\u27s disease. A biopsy of the mass in the hip was performed and Kimura\u27s disease was diagnosed. Treatment with oral prednisolone resulted in a decrease of proteinuria and regression of the subcutaneous mass. Kimura\u27s disease should be included in the differential diagnosis of secondary MN