For downloading the full-text of this article please click here.Background and Objective: Nowadays, beliefs and religious coping are regarded as significant factors in developing psychological comfort and personal adaptation among patients with chronic diseases. This study aimed to evaluate the effect of teaching Islamic-based coping strategies on women with fibromyalgia in terms of chronic pain and quality of life.Method: The research design was a semi-experimental one with pretest-posttest and control group format. The sample included women with FMS who referred to Pain Clinics of Kermanshah in 2016. After ensuring research entry requirements, they were assessed based on IASP, ACR criteria, Demographic Questionnaires, PIS, CPAQ and WHOQOL-26. Those who got the highest scores were selected via convenience sampling. Then, the participants were randomly divided into experimental and control groups. The data were analyzed using descriptive statistics and multivariate analysis of covariance. In this study, the ethical issues were all considered and the authors declared no conflict of interest.Results: The results indicate a significant difference between the experimental and control groups in reduction of pain intensity and increase in pain acceptance (P<0.05). In addition, the total scores of the quality of life as well as subscales of psychological, physical, social and environmental health were significantly different (P<0.05).Conclusion: Teaching Islamic-based coping strategies affects the chronic pain and quality of life among people with fibromyalgia. As a result, such teachings used in conjunction with standard medical care would have a beneficial effect on health, reducing the severity of clinical disorders.For downloading the full-text of this article please click here