Purpose:To determine the effect of induced myopia and hyperopia in emmetropic eyes using soft contact lenses on retinal parameters, measured by optical coherence tomography.Patients and Methods: In this quasi-experimental self-controlled study 57 emmetropic participants, 18 - 42 years of age, were studied. Each subject underwent a complete ophthalmic examinations including, measurement of best corrected visual acuity, intraocular pressure, dry and cycloplegic refractions, and axial length. Optical coherence tomography scans to measure foveal thickness, parafoveal thickness and perifoveal thickness were performed while different refraction powers were induced in each eye by wearing soft contact lenses of five different diopter (- 10.00, - 5.00, plano, + 5.00, + 10.00).Results: Fifty seven normal emmetropic participants with a mean age of 25.78 ± 6.50 years participated in the present study. Average foveal thickness was 246.02 ± 22.03 μm, 245.47 ± 22.78 μm, 246.47 ± 24.38 μm, 246.42 ± 22.96 μm, and 246.18 ± 22.46 μm in high-induced- myopic (CL: + 10.00 D), mild-induced-myopic (CL: + 5.00 D), emmetropic (CL: Plano), mild-induced-hyperopic (CL: - 5.00 D), and high-induced-hyperopic (CL: - 10.00 D) groups, respectively. Average parafoveal thickness was 329.21 ± 16.31 μm, 329.24 ± 16.36 μm, 328.86 ± 16.46 μm, 328.92 ± 16.57 μm, and 328.80 ± 16.76 μm in high-induced-myopic, mild-induced-myopic, emmetropic, mild-induced-hyperopic, and high-induced-hyperopic groups, respectively. Corresponding numbers for perifoveal thickness was 312.25 ± 14.39 μm, 311.84 ± 14.91 μm, 312.46 ± 16.55 μm, 311.57 ± 14.88 μm, and 311.77 ± 14.96 μm. Conclusion: Contact lens induced myopia and hyperopia had no significant effect on foveal thickness,parafovealthickness and perifoveal thickness readings in Fourier domain optical coherence tomography.Keywords: Optical coherence tomography; myopia; hyperopia; retinal parameters; contact lens.
