In Vivo Hypoglycaemic Effects Of Several Traditional Herbal Medicines On Mouse Model

Abstract

Diabetes mellitus is a common worldwide disease with hyperglycaemia due to abnormal activities ofinsullin. The use of traditional medicine in treatment of diabetes has gained more attention recently because of its convenience. In this study, the hypoglycaemic effects of the ethanol extracts from water okra fruit, methi seeds, Coptis teeta Wall (hoanglien) roots and Kombucha tea are carried out on diabetic mouse model induced by alloxan. Results show that water okra fruits (at 40 g/kg), methi seeds (at 30 g/kg) and hoang lien roots (at 150 mg/kg) posess hypoglycaemia effect. Especially, water okra fruits and hoang lien roots reduce blood glucose from the high level (> 500 mg/dl) to normal level (< 200 mg/dl) without affecting mouse normal physiology. Thus, we conclude that the extracts of water okra fruits, methi seeds and hoang lien roots have the anti-hyperglycaemic effects in diabetes