The Tropics havelong been associated with exotic diseases and epidemics. This historical imaginary arose with Aristotle’s notion of the tropics as the ‘torrid zone’, a geographical regionvirtually uninhabitable to temperatepeoples due to the hostility of its climate,andpersisted in colonial imaginaries of the tropics as pestilential latitudesrequiring slave labour.The tropical sites of colonialism gave rise to urgent studies of tropical diseases which lead to (racialised) changes in urban planning. The Tropics as a region of pandemic, plague and pestilence has been challenged during the COVID-19 pandemic. The novel coronavirus did not(simply)originate in the tropics, nor have peoples of the tropics been specifically or exclusively infected. The papers collected in this Special Issue disruptthe imaginary of pandemics, plague and pestilence in association with the tropics throughcritical, nuanced, and situated inquiriesfromcultural history, ethnography,cultural studies, science and technology studies, Indigenous knowledge, philosophy, anthropology, urban studies, cultural geography, literature and filmanalyses, and expressed throughdistinctiveacademic articles, poetry and speculative fiction