Borden SA

Fiedler HP

Goodfellow M

Graf E

Irran E

Keller S

Nicholson G

Schneider K

Stainsby FM

Sussmuth RD

Bendigoles A similar to C are the first secondary metabolites to be isolated from a member of the actinomycete genus Gordonia. They were detected in a culture filtrate extract of Gordonia australis Acta 2299 by HPLC-diode array analysis and characterized as new steroids by mass spectrometry and NMR experiments. Bendigole C show binding affinity to the human progesterone and A-C to androgen receptor but are inactive at mineralocorticoid and estrogen receptors. In in vitro transactivation studies bendigoles A and C showed moderate and weak androgenic activities

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Bendigoles A~C, New Steroids from <em>Gordonia australis</em> Acta 2299

Bendigoles A~C, New Steroids from <em>Gordonia australis</em> Acta 2299

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