With the sponsorship of ``Fundacio La Caixa'' we met in Barcelona, November
21st and 22nd, to analyze the reasons why, after the completion of the human
genome sequence, the identification all protein coding genes and their variants
remains a distant goal. Here we report on our discussions and summarize some of
the major challenges that need to be overcome in order to complete the human
gene catalog.Comment: Report and discussion resulting from the `Fundacio La Caixa' gene
finding meeting held November 21 and 22 2003 in Barcelon