We investigate cyclohexane dehydrogenation on Pt(111) by performing total energy calculations based on the density functional theory (DFT). After interacting with the Pt, the Pt draws an H atom from the cyclohexane, and an H-Pt bond is formed. With the C-H bond broken, cyclohexyl intermediate (C 6H11) desorbs from Pt(111). The cleaved H atom, then, moves to the hollow site of Pt(111), and the desorbing cyclohexyl comes back to and adsorbs on Pt(111). The C-H bond cleavage requires an activation barrier of 1.18 eV, which is a little lower than that with a small Pt cluster