Study of biocolloids by radiospectroscopic methods (interactions of phospholipid vesicles with polynucleotides)

Abstract

Radiospectroscopic methods were used to study the interactions of phospholipid vesicles with polyadenylic and polyuridylic acids in the presence of bivalent cations of magnesium. The possibility of complex formation between vesicles and poly-A:U duplex as well as the role of magnesium ions in this process were demonstrated. Magnesium cations form bridges between phosphate surface groups of bilayer and the residues of phosphoric acid of the polynucleotides. The structural changes in biocolloid particles during the formation of triple complexes were observed. © 1997 Akadémiai Kiado,