Ovarian cancer is the seventh most common cancer among women, accounting for about 4% of all cancers associated with women. This is a descriptive cross-sectional study based on extraction of cancer incidence data and cancer mortality rates from the Global Cancer Data in 2018. The incidence and mortality rates and ovarian cancer distribution maps were drawn for World countries. To analyze data, correlation test and regression tests were used to evaluate the correlation between its incidence and mortality with HDI. The results showed that there was a positive and significant correlation between ovarian cancer incidence (R = 0.409, P <0.0001) and mortality (R = 0.193, P <0.05) with HDI. The results showed that there was a positive and significant correlation between incidence with GNI ,MYS ,LEB and EYS ( P <0.0001). The results also demonstrated that there was a positive and significant correlation between mortality and GNI, MYS, LEB and EYS ( P <0.05).The linear regression model showed that a higher MYS [B = 0.2, CI95%: (- 0.03,0.5)] significantly increased the incidence of ovarian cancer and increased MYS [B = 0.2, CI95% (0.03, 0.4)] increased mortality. Given the positive and significant correlation between ovarian cancer incidence and mortality with HDI, attention to risk factors in these countries can be effective in curbing its incidence and mortality