Annen, L.

de Gelder, B.

Hodiamont, P.P.G.

Masthoff, E.D.

Trompenaars, F.

Vroomen, J.

English

Tilburg University Repository

    Tilburg UniversityIntact and impaired intersensory integration in schizophrenia (abstract)de Gelder, B.; Vroomen, J.; Annen, L.; Trompenaars, F.; Masthoff, E.D.; Hodiamont, P.P.G.Published in:Schizophrenia ResearchPublication date:2000Document VersionPublisher's PDF, also known as Version of recordLink to publication in Tilburg University Research PortalCitation for published version (APA):de Gelder, B., Vroomen, J., Annen, L., Trompenaars, F., Masthoff, E. D., & Hodiamont, P. P. G. (2000). Intactand impaired intersensory integration in schizophrenia (abstract). Schizophrenia Research, 41, 14.General rightsCopyright and moral rights for the publications made accessible in the public portal are retained by the authors and/or other copyright ownersand it is a condition of accessing publications that users recognise and abide by the legal requirements associated with these rights.            • Users may download and print one copy of any publication from the public portal for the purpose of private study or research.            • You may not further distribute the material or use it for any profit-making activity or commercial gain            • You may freely distribute the URL identifying the publication in the public portalTake down policyIf you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediatelyand investigate your claim.Download date: 12. May. 202114 Oral Session VI Is There a Core Variable Underlying Cognitive Deficits? I N T A C T  A N D  I M P A I R E D  I N T E R S E N S O R Y  I N T E G R A T I O N  I N  S C H I Z O P H R E N I A  B. de Ge lde r  1.2, j .  V r o o m e n  1, L. A n n e n  a F.  T r o m p e n a a r s ,  E. M a s t h o f ,  P. H o d i a m o n t  1,3 1 Cognitive Neuroscience Laboratory, Tilburg University, The Netherlands 2 Laboratory ofNeurophysiology, UCL, Belgium s Mental Health Center, Brabant, The Netherlands" Integration of  information from provided simultaneously by different sensory channels (audition and vision) was studied in a group of  schizophrenic patients. Three tasks were adminis- tered that each focus on one aspect of audiovisual integration. The first task was intended to assess audiovisual interactions in spatial localization of sounds (ventriloquism). The second and third tasks focused on the integration of the information provided by two separate input channels and measured cross- modal bias. One task was a variant of  the McGurk phenomenon (impact of incongruent lip movements on perception of speech sounds) and the other investigated how rating of  a facial expression is biased by a congruent or incongruent (de Gelder and Vroomen, in press; de Gelder et al., 1999) tone of voice. The subjects consisted of a group of 16 schizophrenic patients. Diagnosis was conform DSM IV. Criteria for inclusion in the study were based on results obtained the SCAN (Schedules for Clinical Assessment in Neuropsychiatry). Results were compared with a control group consisting of  normal adults of comparable educational level. The results show an entirely normal pattern of performance in the first but not in the second and third task. In sharp contrast to the controls, the schizophrenic patients did not provide evidence of integration of the two inputs. While the results were not different from the normal pattern for presenta- tion of each input in isolation it appeared that in the bi-modal condition whether of speech or of affective information none of the schizophrenic patients showed evidence of combining the two input channels. F A L S E  M E M O R I E S  I N  S C H I Z O P H R E N I A :  A N  E X P E R I M E N T A L  A P P R O A C H  C. H u r o n ,  J .M.  D a n i o n  CNRS UMR 7593, Pavillon Cldrambault, Htpital de la Pitid SalpOtri~re. 47 bd de rhdpital, 75013 Paris, France Knowing whether autobiographical memories reported by patients with schizophrenia correspond to events that did actually occur or are memory illusions is critical for clinicians. Recent studies have described an experimental procedure which allows to investigate the production of false memories. The aim of this study was to investigate false recognition and related states of awareness using a procedure which elicited numerous false memories. Method: 30 patients with schizophrenia and 30 normal subjects studied lists of words semantically related to a non-presented theme word (critical lure). On a recognition memory task with both previously presented words and non-presented critical lures, subjects gave Remember responses to recognized items that were accompanied by conscious recollection, Know responses to items that were recognized on the basis of familiarity and Guess responses to items that were produced by guessing. Results: Schizophrenia impaired false recognition to the same extent as true recognition. This deficit was restricted to memo- ries associated with conscious recollection. Conclusions: These results suggest that a common mecha- nism, such as defective organizational processes at encoding, could account of the impairment of conscious recollection associated with both true and false recognition in schizophrenia. They indicate that schizophrenia impairs true and false episodic memories in that they are mental constructions of past events rather than literal records of  these events. I M P A I R E D  A T T E N T I O N  D O E S  N O T  C A U S E  P S Y C H O T I C  S Y M P T O M S  J .H.  Wil l iams,  N .A .  Wel lman ,  D.P.  Geaney ,  J .N.P .  Rawl ins  OPTIMA, Radcliffe Infirmary, Woodstock Road, Oxford, 0)(2 6HE, UK Background: Many patients with schizophrenia appear dis- tractible, clinically. However, no previous studies have tested if clinical distractibility relates to experimental measures of attention. Stroop interference (SI) provides an experimental measure of  sensitivity to distractors. More SI indexes more distractibility in healthy people: we tested if clinical distractibil- ity relates to larger SI in psychosis. Methods: 41 dextral patients took part: 29 had schizophrenia ( ICD- 10) and 12 had affective psychoses. 20/41 were treatment- naive (14 schizophrenic), the rest were taking only antipsychot- ics. The patients completed a computerised Stroop test and a structural interview that included a rating of  clinical dis- tractibility. Results: Surprisingly, SI correlated inversely with clinical distractibility: patients who were clinically distractible had less SI than those who were not. SI was absent in drug-naive patients who were clinically distractible. Overall, schizophrenic patients taking antipsychotics showed more SI than those who were drug-naive; however, patients with affective psychoses showed the opposite pattern. 

Intact and impaired intersensory integration in schizophrenia (abstract)

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Intact and impaired intersensory integration in schizophrenia (abstract)

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