Akhter SA

Brodde OE

Coupry I

Duzic E

Eason MG

Gellman RL

Green SA

Gulick J

Lafontan M

Langer SZ

Link R

Link RE

Lomasney JW

Mansier P

Neubauer GE

Pelzer S

Perez DM

Sallinen J

Schwinn DA

Shen YT

Strader CD

Susulic VS

Wood SA

Wu D

Xiao RP

 ▪ Abstract  Adrenergic receptors are key targets within the autonomic nervous system, regulating a wide variety of physiological processes. The ability to modify adrenergic receptor expression patterns in vivo has added a powerful new tool to the functional analysis of these receptors. Modification of adrenergic receptor gene expression by overexpression, genetic ablation, or site-specific mutation has added new insight to models of receptor coupling behavior, pharmacology, and subtype-specific physiological function. This review highlights some of the recent advances resulting from such genetic approaches to the study of adrenergic receptors. </jats:p

Daniel K. Rohrer

Brian K. Kobilka

Crossref

The Annual Review of Pharmacology and Toxicology

INSIGHTS FROM IN VIVO MODIFICATION OF ADRENERGIC RECEPTOR GENE EXPRESSION

INSIGHTS FROM IN VIVO MODIFICATION OF ADRENERGIC RECEPTOR GENE EXPRESSION

Abstract

Similar works

Full text

Available Versions

Crossref