The DNA molecule is modeled by a parabola embedded chain with long-range
interactions between twisted base pair dipoles. A mechanism for bubble
generation is presented and investigated in two different configurations. Using
random normally distributed initial conditions to simulate thermal
fluctuations, a relationship between bubble generation, twist and curvature is
established. An analytical approach supports the numerical results.Comment: 7 pages, 8 figures. Accepted for Phys. Rev. E (in press
