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Organ printing as an information technology
Authors
Brian
Buehler
+21 more
Cranford
da Silva JV1
Das
Forgacs
Gilberto
Jorge Vicente Lopes da Silva
Karoly Jakab
Kasyanov
Kasyanov
Mironov
Park JS1
Patil
Rodrigo A. Rezende
Skylar Tibbits
Sun
Tomoaki Nagaoka
Vladimir Kasyanov
Vladimir Mironov
Yang
Yang
Zhang SX1
Publication date
1 January 2015
Publisher
'Elsevier BV'
Doi
Cite
Abstract
Funding Information: This work has been sponsored by the São Paulo Research Foundation (FAPESP), The Brazilian Institute of Biofabrication (INCT-BIOFABRIS) and National Council for Scientific and Technological Development (CNPq). Publisher Copyright: © 2015 Published by Elsevier Ltd.Organ printing is defined as a layer by layer additive robotic computer-aided biofabrication of functional 3D organ constructs with using self-assembling tissue spheroids according to digital model. Information technology and computer-aided design softwares are instrumental in the transformation of virtual 3D bioimaging information about human tissue and organs into living biological reality during 3D bioprinting. Information technology enables design blueprints for bioprinting of human organs as well as predictive computer simulation both printing and post-printing processes. 3D bioprinting is now considered as an emerging information technology and the effective application of existing information technology tools and development of new technological platforms such as human tissue and organ informatics, design automation, virtual human organs, virtual organ biofabrication line, mathematical modeling and predictive computer simulations of bioprinted tissue fusion and maturation is an important technological imperative for advancing organ bioprinting.publishersversionPeer reviewe
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