Life After Critical Illness: Neurocognitive Functioning and Health-Related Quality of Life of Children After PICU Admission, and the Role of Late Parenteral Nutrition

Abstract

The results of the PEPaNIC (pediatric early versus late parenteral nutrition in the pediatric intensive care unit) follow-up study are described in this dissertation. Neurocognitive functioning of children who participated in the PEPaNIC randomized controlled trial was assessed two and four years after admission to the intensive care. Health-related quality of life of children and parents was assessed six months and two years after admission to the pediatric intensive care unit. In addition to the comparison between patients who received early versus late parenteral nutrition, the group of critically ill children was compared with a group of healthy control children