The Grey Zones of the Management ofGastric Cancer. Consensus Statements from the Gastric CancerItalian Network (GAIN

Alfredo, Falcone

Andrea, Spallanzani

D'Ugo, Domenico (ORCID:0000-0001-6657-6318)

Ferdinando de Vita,

Giuseppe, Tirino

Lorenzo, Fornaro1

Lorenzon, Laura

Stefano, Cascinu

English

Background: Management of gastric and gastroesophageal junction (GEJ) adenocarcinoma remains challenging, because of the heterogeneity in tumor biology within the upper gastrointestinal tract. Daily clinical practice is full of grey areas regarding the complexity of diagnostic, staging, and therapeutic procedures. The aim of this paper is to provide a guide for clinicians facing challenging situations in routine practice, taking a multidisciplinary consensus approach based on available literature. Methods: The GAIN (GAstric cancer Italian Network) group was established with the aims of reviewing literature evidence, discussing key issues in prevention, diagnosis, and management of gastric and GEJ adenocarcinoma, and offering a summary of statements. A Delphi consensus method was used to obtain opinions from the expert panel of specialists. Results: Forty-nine clinical questions were identified in six areas of interest: role of multidisciplinary team; risk factors; diagnosis; management of early gastric cancer and multimodal approach to localized gastric cancer; treatment of elderly patients with locally advanced resectable disease; and treatment of locally advanced and metastatic cancer. Conclusions: The statements presented may guide clinicians in practical management of this disease

Fornaro, Lorenzo

Spallanzani, Andrea

de Vita, Ferdinando

D'Ugo, Domenico

Falcone, Alfredo

Tirino, Giuseppe

Cascinu, Stefano

Archivio Istituzionale della Ricerca - Università degli Studi della Campania "Luigi Vanvitelli"

Beyond the Guidelines: The Grey Zones of the Management of Gastric Cancer. Consensus Statements from the Gastric Cancer Italian Network (GAIN)

Domenico D’Ugo

Laura Lorenzon

PubliCatt

Beyond the Guidelines: The Grey Zones of the Management ofGastric Cancer. Consensus Statements from the Gastric CancerItalian Network (GAIN)

Beyond the Guidelines: The Grey Zones of the Management ofGastric Cancer. Consensus Statements from the Gastric CancerItalian Network (GAIN)

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Archivio Istituzionale della Ricerca - Università degli Studi della Campania "Luigi Vanvitelli"

PubliCatt

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