A microstructured membrane reactor has been developed to overcome the safety and productivity challenge of the direct synthesis of hydrogen peroxide. A single membrane is employed for separate, continuous dosage of the gaseous reactants hydrogen and oxygen to the solid catalyst present in the aqueous solvent. Using a custom OpenFOAM® model, the impact of catalyst‐coated static mixers with different mixer geometries is studied. It is demonstrated that the custom fluid guiding elements outperform the investigated commercial static mixer under the flow conditions relevant to this application