The American Society for Biochemistry and Molecular Biology
Abstract
Background: Novel therapeutic approaches against influenza are required. Bakuchiol is a phenolic isoprenoid found in Babchi seeds.
Results: Bakuchiol enantiomer-selectively inhibited influenza A viral infection and growth and activated the Nrf2 pathway.
Conclusion: Bakuchiol showed novel enantiomer-selective anti-influenza viral activity.
Significance: The study of bakuchiol will contribute to the development of novel approaches to influenza therapy
