PLATELET AGGREGATION AFTER EXPERIMENTAL BURN INJURY AND THERAPY

Abstract

Based on data concerning the coagulation changes after thermal injury the authors studied platelet aggregation after burn and its treatment. Severe thermal injury of Ha and lib degree was inflicted in white male rats (200 ±20 g b. m.) under aether anaesthesia. It ranged over 17,5 ± 2,5 % of the body surface. The animals were divided into the following groups: 1) burned non-treated; 2) burned and treated with Sol. Hartmanni (Hr), 3) burned and treated with Hemodex (Hx), and 4) controls. The treatment was intraperitoneally carried out immediately after the injury as well as on 6th and 24th hour after it. An elevation of the platelet aggregation for all the groups on the 24th hour after the injury was established

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