The study aimed to engage Nigerian maternal, newborn, and child health (MNCH) policy-makers and stakeholders and to assess their existing knowledge and capacity on the use of research evidence for policy-making and practice. A total of 40 participants completed the questionnaire. The outcomes suggest that a future stakeholders’ engagement event could serve as an important platform to assess policy-makers’ capacity for evidence-informed policy-making. Constraints to capacity include lack of access to, and inability to synthesize, adapt and utilize available research evidence