Not AvailableMungbean is affected by several diseases incited by viruses,
fungi, bacteria and nematodes. In this study, coat-protein
sequence was analyzed and modelled to explore properties and
structure of Mungbean yellow mosaic India virus (MYMIV).
Since no structural information is available for majority of
pro tein sequenc es a vailable in Protein Data Bank,
computational methods for protein structure prediction have
been of much interest in recent years. Physico-chemical
properties of the protein under study were computed. The grand
average of hydropathy (GRAVY) value and instability index
were found to be -0.646 and 45.75, respectively, supporting the
protein to have better interaction with water. Comparative
homology modelling was performed with ModWeb, ESyPred
and Swiss Model. It was observed that the model generated by
ModWeb was most acceptable with 90.2% of the residues in
most favoured region. The model was validated using Structural
Analysis and Verification Server (SAVS). Coat-protein
struc ture of MYMIV obtained throug h computational
modelling was found congruent with their protein structure
obtained by X-ray crystallography or NMR.Not Availabl
