BACKGROUND:
Diabetes is a common and serious disease leading to chronic, mostly irreversible macro and microvascular complications. Silent myocardial ischemia common in diabetic patients because of autonomic neuropathy. Microalbuminuria is one if the important risk factor for endothelial dysfunction that leads to coronary artery disease. So we decided to correlate microalbuminuria with asymptomatic myocardial ischemia.
METHODS:
50 patients attending diabetic OPD at Government Vellore medical college and hospital were studied. Asymptomatic patients with no symptoms or history of ischemic heart disease and normal ECG with microalbuminuria were enrolled in this study. A complete clinical examination was done.
RESULTS:
Out of 50 diabetic patients with microlbuminuria in my study. Treadmill exercise test positive cases were 32 (64%) and negative cases were 18(36%) patients, which implies that microalbuminuria is an independent risk factor for SMI. 13 patients with diabetes duration more than 10 years, Treadmill test was positive in all 13 patients (100%). Duration of DM significantly associated with SMI.
30 patients with diabetes duration between 6-10 years. Treadmill test was positive in 19 patients (63.3%).
7 patients with diabetes duration of less than or equal to 5 years. Treadmill test positive in 5 (71.4%).
CONCLUSIONS:
Hence, in this study it was observed that longer the duration of diabetes with microalbuminuria, greater is the predisposition for silent myocardial ischemia. In the present study, 64% of asymptomatic patients with microalbuminuria had a positive treadmill exercise test. Hence, we concluded from this study that microalbuminuria is an independent risk factor for silent myocardial ischemia
