This project’s overall objective was to create a self-sustaining regional operations research (OR) training and research center for South Asia at the International Institute of Population Sciences (IIPS), in Mumbai, India. The goal was to institutionalize operations research (OR) in IIPS by building the teaching and research capabilities of the faculty and research team. Capacity building was accomplished through a training of trainers that included an OR workshop in Nepal, two four-day OR workshops for program managers, one ten-day OR workshop for researchers, and a four-day scientific-writing course for researchers and program managers to provide guidelines for preparing research articles and reports. Nine OR studies were carried out, and 12 articles were published in peer-reviewed national and international journals. As noted in this report, capacity-building activities also produced an important multiplier effect in three additional organizations: The National Institute of Health and Family Welfare (NIHFW), New Delhi, India, the Center for Operations Research Training, Vadodara, India, and the Medical College of Ahmadabad, India