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Acid Sphingomyelinase Regulates the Localization and Trafficking of Palmitoylated Proteins

Abstract

In human, loss of Acid Sphingomeylinase (ASM/SMPD1) causes Niemann-Pick Disease, type A. ASM hydrolyzes sphingomyelins to produce ceramides but protein targets of ASM remain largely unclear. ... See full text for complete abstract

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