Benzimidazoles are play an important role in medical field with so many pharmacological activities such as like anti-microbial, anti-viral, anti-diabetic, anti-cancer, antioxidant, anti-parasitic, antihelmintics, antiproliferative, anti-HIV, anticonvulsant, analgesic, antiinflammatory, antihypertensive, antineoplastic, proton pump inhibitor, antitrichinellosis  and other pharmacological activities. Benzimidazoles are remarkably effective compounds, extensive biochemical and pharmacological studies have confirmed that these molecules are effective against various strains of microorganisms. Different substituted benzimidazoles having anti-microbial activities. These activities encouraged the development of some more potent and significant compounds
