Leiomyoma is a benign tumor arising from smooth muscle of hollow organs viz. uterus, vagina, intestines, stomach, urinary bladder and esophagus and is common in cow, dogs and fowl. Leiomyoma have slow-growing behaviour, localli invasive, malignant tumor of smooth muscle origin that typically is slow to metastasize4

Arifah, Sukmasari

Noviana, Deni

Suwito, Benda A

Syahnita, Osye

Zulfiati, Eva

English

Scientific Journals of Bogor Agricultural University

 538 | Proc. of the 20th FAVA CONGRESS & The 15th KIVNAS PDHI, Bali Nov 1-3,  2018 Poster Presentation (PF-14)  Gastric Leiomyoma in a Twelve Year Old Pulli dog – A Case Report  Siti Zaenab1*, Osye Syahnita1, Eva Zulfiati1, Benda Alifianti Suwito1, Sukmasari Arifah1, Deni Noviana2  1My Vets Animal Clinic Kemang 2Animal Teaching Hospital, Faculty of Veterinary Medicine Bogor Agricultural University  *corresponding author Corresponding email: myvets001@gmail.com  Keywords: leiomyoma, neoplasia, tumor.    INTRODUCTION Leiomyoma is a benign tumor arising from smooth muscle of hollow organs viz. uterus, vagina, intestines, stomach, urinary bladder and esophagus and is common in cow, dogs and fowl. Leiomyoma have slow-growing behaviour, localli invasive, malignant tumor of smooth muscle origin that typically is slow to metastasize4.  CASE REPORT  Signalment, anamneses, and clinical signs. A twelve year old Pulli dog was reffered to My Vets Animal Clinic Clinic and Animal Teaching Hospital Faculty of Veterinary Medicine Bogor Agricultural University to do ultrasound with history of frequently vomiting and diarrhea. Ultrasound examination revealed mass between gastric, liver, and spleen measuring 3,416 cm. Physical examination. On physical examinaton patient showed a bit lethargy, palpation abdomen tense and had abdominal pain. Differential diagnose. Differential diagnoses include many systemic disease (uremia, inflammatory disease), nonneoplastic disease (foreign body, mucosal hypertrophy). Diagnose. The diagnose could be made ultrasonographically assosiated with a mix echogenity (anechoic-hypoechoic) structure. Laboratory findings usually are not spesific. Prognosis. Prognosis depends on identification and treatment underlying diseases. The prognosis is good if there is no perforation and peritonitis. Treatment. Pre surgery was done by giving intravena fluid by vena cephalica, cefotaxime intravena injection (30 mg/kg BW) and pethidine sub cutan injection (2 mg/kg BW). Surgical correction was attempted under general anaesthetics using combination of ketamine (10 mg/kg BW) and diazepam (0,5 mg/kg BW) as preanaesthesia and isoflurane as inhalation anaesthetics. Food should be withheld for 12 hours before surgery. An exploratory laparotomy was performed to remove the greater curvature of the stomach, Ligate the branch of the right and left gastric artery and vein  Figure1. Explore the stomach  Figure 2. Ligate the branch of the right and left gastric artery  After removal of the suspect tissue, leaving 2 cm margins of normal tissue, perform a two-layer end-to-end anastomosis of the stomach. Close the mucosa and submucosa of the dorsal surface of the stomach in a simple continuous pattern using  3-0 monofilament absorbable suture, close the serosa and muscularis layers in a simple continuous  using the same suture.  Figure 3. Removing the suspect tissue   Proc. of the 20th FAVA CONGRESS & The 15th KIVNAS PDHI, Bali Nov 1-3,  2018 | 539 Figure 4. Suturing the incision area  Post treatment. Electrolyte was monitored after the surgery and soft low fat nutrition was given until 3 days post surgery. Biopsi was done and the result revealed the mass in the stomach as neoplasia leiomyoma. Ultrasonographs was performed two months post surgery and so on, in order to confirm no metastasis to other organ (liver and spleen).  DISCUSSION  Gastrointestine mesenchymal tumors are currently divided into Gastrointestinal stromal tumor (GITs) and leiomyoma/sarcoma. Both this tumor constitute the majority of mesenchymal tumors of the GI tract and most common found in the stomach and smal intestine. In this case the tumor confirmed pathologically as leiomyoma1. Surgery is the primary treatment of choice in localized or potentially resectable. It is imperative to avoid tumor rupture. The tumors are fragile and should be handled with care, with an aim to achieve complete gross resection of the tumor with an intact pseudocapsule5. It is important to identify between normal tissue and damage tissue, carefully remove the suspected tissue and leave margin 2 cm from normal tissue. Considering underlying disease such as liver changes related to chronic metabolism disorder, nutrition and supplementation for hepatoprotectant are needed postoperatively.  CONCLUSION Leiomyoma are the most common benign canine gastric tumor with almost no clinical signs appear until the tumors are large. Considering to prevent metastasis of its tissue it is important to leave a margin between the suspect tissue and normal2. Food intake should be monitored moderate amounts of protein  and carbohydrate and low fat1.  REFERENCES [1] Fossum,T.W., Dewey, C.W., Horn, C.V., Johnson, A.L., M.Macphail, C., Radlinsky, M.G., Schulz, K.S., dan Willard, M.D. 2013. Small Animal Surgery, Fourth Edition. Mosby Inc., USA. [2] T. Nishida and S. Hirota, “Biological and clinical review of stromal tumors in the gastrointestinal tract,” Histology and Histopathology, vol. 15, no. 4, pp. 1293–1301, 2000. [3] Sastry GA. 1983. Veterinary Pathology. Neoplasms. Delhi. CBS publishers and distributors. pp. 232-233. [4] Pidhorecky I, Cheney RT, Kraybill WG, Gibbs JF. Gastrointestinal stromal tumors: current diagnosis, biologic behavior, and management. Ann Surg Oncol. 2000;7:705–712. [PubMed].   

PF-14 Gastric Leiomyoma in a Twelve Year Old Pulli dog – A Case Report

Hemera Zoa

http://journal.ipb.ac.id/index.php/hemera/article/download/23882/15751

PF-14 Gastric Leiomyoma in a Twelve Year Old Pulli dog – A Case Report

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Scientific Journals of Bogor Agricultural University

Hemera Zoa