Granular cell tumor, also known as Abrikossoff\u27s tumor, is a relatively uncommon benign neoplasm with a histogenesis that is still uncertain. This report describes a case of granular cell tumor that originated at the left lateral border of the tongue in a 21-year-old man. Surgical resection with surrounding tissue was performed under local anesthesia. As a result, the patient has remained free of disease for two years after surgery to date. Histopathological examination of the excised specimens demonstrates strands or sheets of large polygonal tumor cells with eosinophilic granular cytoplasm, with no cellular atypia or anomalous mitotic activity. Immunohistochemically, tumor cells showed reactivity to S 100 protein and neuron-specific enolase (NSE), suggesting Schwann cell origin of the lesion
