The digitization is the first feat of safety, knowledge and management of Cultural Heritage. The technological development has produced a complexity increase to manage the big data acquired. This paper shows the best practices for the digitization of a museum (National Gallery of Marche), hosted in a historical and complex building: it’s a problem of contents and “container” (the Urbino Ducal Palace = a city in the appearance of a Palace). This is the case study of the first challenging aim of the CIVITAS project. The digitization workflow has combined the several sensors and technology at different scales, such as static and mobile wearable laser scanners systems, the different focals for internal and external cameras, 360 panoramas and HD images. The goal achieved is the new 3D digital model, validated and with high accuracy, containing big 3D data, as starting point of HBIM, Serious Games, VR/AR applications.
