The authors thank Dr. Ralston for his interest in our work and for his thought-provoking remarks. We do agree to some extent with his comments regarding the necessity for more understanding of the complex interactions between mercury (Hg) and selenium (Se) with regard to human health. However, our study was constructed based upon the model for risk assessment of mercury in tuna set forth by the U.S. Food and Drug Administration in Yess. This model was chosen because it is the current standard for risk assessment of mercury in tuna and because it is consistent, and therefore comparable to, current literature
