After a brief review of string and M-Theory we point out some deficiencies.
Partly to cure them, we present several arguments for ``F-Theory'', enlarging
spacetime to (2,10) signature, following the original suggestion of C. Vafa.
We introduce a suggestive Supersymmetric 27-plet of particles, associated to
the exceptional symmetric hermitian space E6/Spinc(10). Several
possible future directions, including using projective rather than metric
geometry, are mentioned. We should emphasize that F-Theory is yet just a very
provisional attempt, lacking clear dynamical principles.Comment: To appear in early 2006 in Mod. Phys. Lett. A as Brief Revie