We consider the U(1) problem within the AdS/CFT framework. We explain how the
Witten-Veneziano formula for the eta' mass is related to a generalized
Green-Schwarz mechanism. The closed string mode, that cancels the anomaly of
the gauged U(1) axial symmetry, is identified with the eta' meson. In a
particular set-up of D3-branes on a C3/(Z3xZ3) orbifold singularity, the eta'
meson is a twisted-sector R-R field.Comment: 10 pages, LaTex. 1 eps figure. v2: minor changes, refs. added, to
appear in JHE