The aim of this study was to investigate the effect of supplementing standard diets for pregnant and lactating sows with live yeast culture (Saccharomyces cerevisiae) on their health status, as well as the health status and growth parameters of their litters during lactation. A total of 120 sows were divided into three groups: the first group was fed diets supplemented with probiotics during pregnancy (G+P, n=40), the second group was fed these diets during lactation (L+P, n=40), and the third group was the control group which was not fed diets supplemented with probiotics (C, n = 40). During the lactation period, a significantly (p<0.01) smaller proportion of probiotic treated sows (G+P=7.5%, L+P=12.5%) manifested clinical signs of the uterus and/or the udder disease in comparison with the control sows (22.5%). The incidence of infectious diarrhea in the nursing piglets was significantly (p<0.05) lower in the treated sows (12.5%) compared to the control sows (27.5 %). The average number of weaned piglets per litter (p/l) and average litter weight at weaning (lw) (G+P=11.6 p/l and 103.6 kg lw, L+P=11.1 p/l and 102.8 kg lw, C=10 p/l and 79 kg lw) were significantly higher (p<0.01 or p<0.05) in sows treated with probiotic compared to the control sows. These results clearly show that the use of probiotic significantly improves the health status of sows and nursing piglets, as well as the piglets growth parameters
