In the last three decades, a number of studies have been undertaken concerning the impact of science and technological innovations on health sector reforms and responsive healthcare delivery in most countries globally. However, few of these studies are placed in historical context and/or focused particularly on the case of Ghana. In addition, such studies are mostly carried out in the biomedical and physical sciences with very few in the social sciences. Against this background, this paper draws experiences from health professionals in purposively selected institutions in Ghana and supported with critical review of related literature, to answer two central research questions. First, how has science and technological advancement effectively and efficiently supported healthcare delivery system in Ghana? Second, how have post-independence health sector reforms in Ghana been responsive to the needs of patients due to advances in science and technology? Based on empirical results, we argue in this paper that over the last few decades, advances in science and technology have significantly improved Ghana’s health delivery system and promoted responsive healthcare particularly in the area of orthodox medical services. However, the gains from advances in science and technology need to be strengthened by the Ministry of Health, Ghana Health Services and relevant stakeholders to improve health facilities and conditions especially in rural districts in the country
