Three-manifolds can be obtained through surgery of framed links in S3. We
study the meaning of surgery procedures in the context of topological strings.
We obtain U(N) three-manifold invariants from U(N) framed link invariants in
Chern-Simons theory on S3. These three-manifold invariants are proportional
to the trivial connection contribution to the Chern-Simons partition function
on the respective three-manifolds. Using the topological string duality
conjecture, we show that the large N expansion of U(N) Chern-Simons free
energies on three-manifolds, obtained from some class of framed links, have a
closed string expansion. These expansions resemble the closed string A-model
partition functions on Calabi-Yau manifolds with one Kahler parameter. We also
determine Gopakumar-Vafa integer coefficients and Gromov-Witten rational
coefficients corresponding to Chern-Simons free energies on some
three-manifolds.Comment: Some clarifications added. Final version to appear in NP