We discuss type IIB orientifolds with D-branes, and NSNS and RR field
strength fluxes. The D-brane sectors lead to open string spectra with
non-abelian gauge symmetry and charged chiral fermions. The closed string field
strengths generate a scalar potential stabilizing most moduli. We describe the
construction of N=1 supersymmetric models in the context of orientifolds of IIB
theory on T^6/Z_2 x Z_2, containing D9-branes with world-volume magnetic
fluxes, and illustrate model building possibilities with several explicit
examples. We comment on a T-dual picture with D8-branes on non-Calabi-Yau
half-flat geometries, and discuss some of the topological properties of such
configurations. We also explore the construction of models with fluxes and with
D3-branes at singularities and present a non-supersymmetric 3-family SU(5)
model.Comment: latex, 49 pages, 2 figure