This paper reports the parallel screening of zoospore germination and protrusive forces of germ tubes on a labon-a-chip platform, integrating valve-based single zoospore compartmentalization with micropillar force sensing.
Individually-controllable, normally-closed microvalves were optimized to facilitate zoospore compartmentalization
in measurement channels containing traps and sensing pillars. Performance was evaluated using microspheres and
zoospores of the oomycete Achlya bisexualis. By parallelizing the screening, the platform will support fundamental
studies and aid in the discovery of new compounds to control fungal and oomycete pathogens
