The MedAfriCarbon radiocarbon database and its accompanying web application are outcomes of the MedAfrica project — Archaeological deep history and dynamics of Mediterranean Africa, ca. 9600–700 BC. The dataset presented here in Version 1.0 of the database includes 1587 archaeological 14C dates from 368 sites in Mediterranean Africa. The database is unusual because the majority of the dates within it have been annotated with further cultural and environmental variables, notably the presence/absence of different domestic/wild species and particular material culture traits. MedAfriCarbon also includes a publicly-accessible web application that facilitates data exploration and informal analysis