Adolescence is a critical stage for substance abuse initiation, as well as for substance abuse prevention, intervention, and treatment. This report presents tobacco product use, alcohol use, and illicit drug use rates of Nevada’s youths (aged 12-17) compared with youths nationwide as a whole. Most data were retrieved from the Substance Abuse and Mental Health Services Administration (SAMHSA), including the 2008--2009 National Survey on Drug Use and Health (NSDUH) data and Treatment Episode Data Set (TEDS), supplemented with the Centers for Disease Control and Prevention (CDC)’s 2009 Youth Risk Behavior Survey (YRBS) data. Substate data were taken from SAMHSA’s 2006-2008 NSDUH data, the most updated substate data available so far. The 2010 NSDUH state-level data won’t be released by SAMHSA until 2012