ABSTRACT This paper describes the research plans in the SuperAssist project, introducing personal assistants in the care of diabetes patients, assisting the patients themselves, the medical specialists looking after the patients' healthcare, and the technical specialists responsible for maintaining the health of the devices involved. The paper discusses the issues of trust and cooperation as the critical success factors within this multi-user multi-agent (MUMA) project and within the future of agent-based healthcare attempting to increase the self-help abilities of individual patients