Abstract This short report summarises the scientific content and activities of a student-led event, the 1st student symposium by the UK Regional Student Group of the International Society for Computational Biology. The event took place on October 2014

Farzana Rahman

Fatima Vayani

Mehedi Hassan

Rohit Farmer

Sayoni Das

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Meeting report
Highlights from the 1st Student Symposium on
Computational Biology and Life Sciences, organised
by ISCB Regional Student Group, UK
Farzana Rahman1, Rohit Farmer 2, Sayoni Das 3, Fatima Vayani 4, Mehedi Hassan 1*
Abstract
This short report summarises the scientific content and activities of a student-led event, the 1st student
symposium by the UK Regional Student Group of the International Society for Computational Biology. The event
took place on October 2014.
Keywords
meeting report — ISCB — Student Council — Regional Student Group
1Genomics and Computational Biology Research Group, University of South Wales, CF371DL, UK
2School of Biosciences, University of Birmingham, Birmingham, B152TT, UK
3Research Department of Structural and Molecular Biology, UCL, WC1E6BT, UK
4Algorithms and Bioinformatics Group, King’s College London, UK
*Corresponding author: imehedi@iscb.org
Contents
Background 1
The Event 1
Highlights 2
Award Winners 3
Conclusion 3
Future Editions 3
Acknowledgments 3
References 3
Background
The UK Regional Student Group (RSG UK) of the Interna-
tional Society for Computational Biology is part of the global
network of students and early stage post-doctoral researchers.
The group was formed in December 2013, with a vision to
strengthen and enhance the existing young computational bi-
ologists’ network through dynamic activities. We felt the urge
to initiate a platform for tomorrow’s computational biologists
in the United Kingdom and took the inspirations from similar
initiatives to form our group[1, 2]. We aim to build a wider
network to promote next generation of computational biolo-
gists in the UK.
Our current leadership and members include research stu-
dents and postdoctoral researchers from computational biol-
ogy and life sciences backgrounds. The community offers
networking, soft skill enhancement opportunities for both un-
dergraduate and post-graduate students, and to develop the
relationship between young computational biologists and aca-
demic/industry partners within UK.
1st Student Symposium on
Computational Biology and Life Sciences
The inaugural event of scientific networking activity of the
group was the 1st Student Symposium on Computational
Biology and Life Science on 8th October 2014. The event
took place at the University of South Wales, UK. The sympo-
sium took inspirations from the workshops and conferences
arranged by the ISCB Student Council and its regional stu-
dent groups across the globe [3, 4, 5]. Fujitsu Ltd, a global
provider of information technology services and HPCWales, a
pan-wales supercomputing infrastructure, supported the event.
Scope and format of the meeting
The main scope of this meeting was to create opportunities
for students and young researchers to interact with senior aca-
demics and investigators from all over the UK where they can
discuss ideas, exchange knowledge and build networks. In
addition, four distinguished scientists were invited to deliver
keynote speeches.
The traditional scientific component of the meeting con-
sisted of three sessions of oral presentations by Students and
postdoctoral researchers. The sessions also included four
keynote presentations from senior scientists and one inaugural
presentation on RSGs and their roles.
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Dr Rhobert Lewis from the University of South Wales
gave a welcome note. Dr Manuel Corpas , the founder of
the ISCB Student Council, delivered a keynote to provide
an overview of developing next generation of Computational
Biologists through the Regional Student Groups across the
globe.
Dedicated poster sessions and industrial partner talks took
place during coffee breaks between oral sessions. As part of
the industrial partner talk, Dr Jonathan Mullins, from Molecu-
lomics Ltd., gave a short presentation on generating high-
value genome-scale molecular information to increase and
improve knowledge of interactions between organisms and
chemical compounds using the tools and services developed
by Moleculomics Ltd.
The RSG UK team received more than 20 abstracts from
students who wished to present their work at the symposium.
The submitted abstracts were peer-reviewed by ten indepen-
dent reviewers of which five reviewers were senior academic
and principal investigators and other five reviewers were mid-
career researchers. The reviews selected a total of six abstracts
for oral presentations, and twelve abstracts for poster presen-
tations. Overall, 65 delegates from 24 UK institutions and
industries attended the symposium and the programme.
All abstracts accepted for oral and poster presentations
are available online from http://rsg-uk.iscbsc.org/sym2014/.
List of keynote speakers
Following scientists generously agreed and delivered keynotes
speeches on the day.
• Dr Alex Bateman (EMBL-EBI, Cambridge University)
• Dr Natasha De Vere (National Botanic Garden of Wales)
• Dr Chris Creevey (IEBRS, Aberystwyth University),
• Dr Tatiana Tatarinova (University of Southern Califor-
nia)
Highlights
Keynotes Summary
Dr Natasha de Vere’s keynote speech gave an overview of her
work on DNA Barcoding of Welsh and UK flora to create an
open access resource for people, wildlife and the environment
[6]. In 2012, Dr. de Vere led a team to complete the barcoding
of all of the welsh flora and now working on barcoding all of
the British flora.
The second keynote speech by Dr Alex Bateman under-
lined the impacts of biological databases in modern day com-
putational biology research and highlighted the importance
of the role of bio-curators in biological studies. Dr. Bateman
emphasised the role of biocurators by addressing them as the
”unsung heroes of biology” who orders and make sense of
the immense primary literature for us. He encouraged the
audience in participating contributing to public encyclopaedia
the Wikipedia and shared his recent experiences with some
initiatives to inspire the scientific community in enriching
Wikipedia. [7, 8, 9] In the second part of his talk he gave our
delegates an overview of his career path, which included some
invaluable advise for young researchers hoping to make their
way into a successful research career.
The third keynote speech by Dr Christopher Creevey, high-
lighted development of system-level approaches in under-
standing microbial community interactions by identifying
genomic factors influencing phenotypic changes in organisms
from Bacteria to Eukaryotes. Dr. Creevey’s talk included
the [10] which aims to generate a reference set of rumen mi-
crobial genome sequences. The project surveyed the rumen
bacterial diversity to examine the culturable fraction of the
rumen bacterial microbiome and reported that there are few
novel but many uncultured taxa within the rumen bacterial mi-
crobiome. In addition, they have identified taxa where further
cultivation efforts are clearly required.
Finally, Dr Tatiana Tatarinova’s keynote speech presented
two novel algorithms, GPS [11] and reAdmix [12] to deter-
mine biogeographic origins of individuals. Both methods are
species-independent and were successfully applied to analysis
of humans, plants and animals. Tatiana also told about ex-
citing aspects of bioinformatician’s life, such as field trips to
remote parts of the Earth to find nearly extinct species, studies
of ancient DNA and efforts to analyze and preserve DNA of
disappearing Native Siberians.
Student and Early Career Researchers Presentations
There were two presentations from Post Doctoral research
fellows and four presentations from current Ph.D. students. In
the first post-doctoral talk, Dr Romain Studer from EMBL-
EBI, Cambridge, UK discussed his current research on find-
ing evolutionary pattern of the phosphoproteome in 18 yeast
species. Dr Studer highlighted that till date the investigate of
Phosphoproteome mostly covers model species (e.g. human,
baker’s yeast), and there is a lack of comprehensive phyloge-
netic analysis of phosphorylation. He and his colleagues are
currently working on estimating the evolutionary analysis of
phosphosites in yeast species.
Dr Ranjit Das from Sheffield University gave the second
post-doctoral talk, where he discussed the evolution of miR-
NAs and their targets among hominoid primates. Dr Das is
working on identifying and understanding the uniquely gained
and lost miRNAs within hominoids and its potential implica-
tions.
In the student presentation section, Sam Nicholls from
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Aberystwyth University presented Goldilocks, a Python pack-
age that provides users with functionality for locating suitable
regions with a genome for analysis. Goldilocks package is
available at https://github.com/SamStudio8/goldilocks.
Francesco Rubino from Aberystwyth University gave an
insight into metagenomics analysis of the rumen microbiome
that reveals functional isoforms driven from niche differentia-
tion for nutrient acquisition.
Silvia Bartolucci from Kings College London, presented
a statistical approach to investigate basic, systematic features
exhibited by adaptive immune systems. Silvia’s work focuses
on Dynamical analysis of diluted associative networks: a min-
imal model for the adaptive immune system.
Russel Sutherland from Kings College London presented
their work on tumor grade prediction across multiple adeno-
carcinomas using exome sequencing data.
Award Winners
The High Performance Computing Wales (HPCW) consor-
tium, and Fujitsu Services UK limited sponsored two travel fel-
lowships that were awarded to Silvia Bartolucci and Vasileios
Panagiotis Lenis to attend and present at the Symposium.
A judging committee formed of senior researchers present
at the event, selected three speakers for three awards; one for
the oral presentation and two for poster presentations. Sam
Nicholls from the Aberystwyth University received the best
oral presentation award for his work titled “Goldilocks: Lo-
cating genomic regions that are ‘just right’”.
Danielle Avancini recieved best poster award for his poster
titled “A Molecular Dynamic Web Server for Analysis of
DNA Structure” and the runner up poster award went to Ste-
fani Dritsa for his poster titled “Towards the increase of the
thermostability of a psychrophilic enzyme”.
The oral and poster presentation award were generously
sponsored by the graduate research center of the University
of South Wales, UK. Sam Nicholls, Danielle Avancini and
Stefani Dritsa received F1000 awards for their presentations
at the RSG UK symposium.
In addition to the aforementioned awards, High Perfor-
mance Computing Wales (HPC Wales) chose Karen Sinu
Ting’s work on “Concatabominations: identifying unstable
taxa in morphological and phylogenomic supertrees using
Safe Taxonomic Reduction” that gives Karen to get exclusive
supercomputing access and support from HPC Wales facility.
Conclusion
The initiative of forming RSG UK and hosting the symposium
was highly appreciated among peers, delegates and sponsors.
The quality of the students’ presentations and high profile
keynotes were greatly admired. The participants agreed that
the nature of the symposium and the scope of networking best
suited their interest. Symposium organisers received positive
feedback and comments from senior and junior researchers
alike. Despite being organised by a newly formed group,
with very small initial membership, the attendance was ex-
cellent, which reflects that news of the symposium was well
disseminated. Overall, the symposium was a great success.
Future Editions
The successful completion and turn-around of the 1st sympo-
sium encouraged to organise yearly symposium. The RSG
UK is pleased to announce that the 2nd student symposium
will be organised in 2015 in October at The Genome Analysis
Centre (TGAC), Norwich. The aim is to arrange a sympo-
sium with a dedicated session for bioinformatics workshop.
Further details will be available on RSG UK website http://rsg-
uk.iscbsc.org/.
Acknowledgments
The success of the student symposium organised by RSG
UK hugely depended on the external and internal support
from senior researchers, student lead activity enthusiasts and
sponsors who helped to make the event a great success. Our
special thanks to Prof. Denis Murphy, the faculty advisor
of RSG UK, who encouraged the organisers to make the
event a success since its inception. We are greatly thank-
ful to the following people for their guidance and support in
different aspect of the symposium arrangement Dr Timothy
Ebbels (Imperial College London), Dr Erhan Elhaik (Univer-
sity of Sheffield), Dr Thomas Di Domenico (University of
Cambridge), Dr Owain Kerton ( University of South Wales),
Umesh Nandal (University of Amsterdam), Chinmay Kumar
Dwibedi ( Ume University , Sweden), James Pack and Charlie
Godfrey from HPC Wales, UK and Mehnaz Tabassum Khan
from Khulna University, Bangladesh. Our special gratitude to
Fujitsu Services UK Limited and HPC Wales Constorium or
their financial and logistics support to the event. We would
also like to extend our thanks to the Graduate Research Office
of the University of South Wales, the International Society for
Computational Biology’s Student Council for their continuous
support to make the symposium a great success.
References
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Highlights from the 1st Student Symposium on Computational Biology and Life Sciences, organised by ISCB Regional Student Group, UK

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Highlights from the 1st Student Symposium on Computational Biology and Life Sciences, organised by ISCB Regional Student Group, UK

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