Abstract. The modern high-throughput sequencing methods provide massive amounts of genome-focused, DNA-positioned data. This data is often represented as a function of the DNA coordinate (e.g. coverage). The genome-or chromosome-wide correlations between data from different sources may provide information about functional biological interrelation of the investigated features, e.g., trancription and histone modification. The task to compute the correlation was already successfully solved for interval annotations ([1]) as well as for coverage (functional) data ([2], [3]
