One pot synthesis of dihydroisoxazoles via 1,3-dipolar cycloaddition of nitrile oxides to allyl chloride

Abstract

Nitrile oxides derived from oxidative dehydrogenation of aldoximes by chloramine-T react with allyl chloride to afford 5-(chloromethyl)-3-aryl-4,5-dihydroisoxazoles in good yields. All compounds were characterized by IR, 1 H-NMR, and MS studies