Systemic pro-inflammatory molecule response to acute submaximal exercise in moderately and highly trained athletes

Abstract

Abstract The effect of training status on acute exercise-induced release of pro-inflammatory biomarkers in circulatory system was studied in 10 moderately trained and seven highly trained athletes. The subjects performed an hour of submaximal bicycle exercise at workload equal to ~70% of heart rate reserve. Venous blood samples were collected 15 min before and immediately after the exercise. Intereukin-6, tumor necrosis factor-α, and monocyte chemotactic protein-1 response to exercise was similar in moderately trained and highly trained athletes (2.5 ± 2.4 vs. 1.0 ± 1.0 pg mL , respectively), suggesting that training status had no impact on cytokine and monocyte chemotactic protein-1 post-exercise concentrations with this experimental model