1997). Interestingly, depenstrains carrying the conditional TAF alleles to nondence on TAF145 is conferred by sequences in the basal permissive conditions results in degradation of TFIID promoter rather than the particular activator used (Shen components and the rapid loss of mRNA production. and Green, 1997). Therefore, in contrast to previous studies in yeast that Sequence analysis has revealed some similarity befound only limited roles for TAFs in transcription, we tween three TAFs and the histones H3, H4, and H2B find that the histone-like TAFs are generally require
