ORIENTAL JOURNAL OF CHEMISTRY Synthesis of Benzo[g]quinoxaline-5,10-dione Based Pyridine Derivatives and their Antimycobacterial Activity

Abstract

ABSTRACT Thirteen new compounds belonging to series 2-amino-6-(5,10-dioxo-2,3-diphenyl-5,10-dihydrobenzo[g]quinoxalin-7-yl)-4-(substituted)phenylpyridine-3-carbonitrile (6a-m) were synthesized by multistep synthetic scheme. The newly synthesized compounds were screened for their antimycobacterial activity by L.J. Slope (Conventional) Method. Compound 6h with 4-N(CH 3 ) 2 group at phenyl ring of above mentioned position has been reported as most active antimycobacterial compound and compound 6k with 4-CH 3 substitution at phenyl above mentioned position has been reported as the least active antimycobacterial compound